What was investigated and what was found?
Of 221 evaluation cycles, only 5 reached the stage at which ROSI could be performed. Four clinical pregnancies were reported.
Interpreting the findings
The rate per transfer differs from the rate across all initiated cycles. Safety data are very limited.
How can you prepare for a consultation?
Start a discussion of ROSI research with any previous sperm retrieval and embryology reports. Ask which cells were used and whether reported rates refer to initiated cycles, cycles reaching procedural feasibility or embryo transfers. Clinical pregnancy and live birth are separate outcomes, a distinction that matters when interpreting both effectiveness and safety findings.
