Genetic assessment and PGT · 2026

Non-invasive PGT-A at advanced age: clinical benefit?

Randomized controlled trial · 1189 women

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Non-invasive PGT-A at advanced age: clinical benefit?

What was investigated and what was found?

Selection using DNA in culture medium did not significantly improve ongoing pregnancy or live birth over morphology. Fewer early miscarriages alone do not establish a case for routine use.

Interpreting the findings

Results apply to the enrolled population and tested protocols; they are not a personal success prediction.

How can you prepare for a consultation?

Genetic-testing decisions depend on age, embryo numbers, family history and previous pregnancies. Bring existing reports to your initial consultation; genetic counselling can be incorporated when appropriate.

What does this research mean for your situation?

Let us begin with your diagnosis, previous findings and goals as a couple. You can request an initial consultation with Prof. Dr. Mehmet Çolakoğlu to discuss what this research means for your own situation.

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